Tobias F. Jakobs

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2D-3D slice-to-volume registration for abdominal organs like liver is difficult due to the breathing motion and tissue deformation. The purpose of our approach is to ease CT-fluoroscopy (CT-fluoro) based needle insertion for the Radiofrequency Liver Ablation procedure using high resolution contrasted preoperative data. In this case, low signal-to-noise(More)
Twenty healthy volunteers (ages 18 to 25 years) were tested for their ability to sense the lateral position of the top of their thoracic spine. When moved slowly from side-to-side in the frontal plane with vision occluded and pelvis immobilized, they could sense the position of a midline point on the skin at the T1 level to within 3 mm of a mean center(More)
Selective Internal Radiation Therapy (SIRT) is a new and effective locoregional anticancer therapy for colorectal cancer patients with liver metastases. Markers for prediction of therapy response and prognosis are needed for the individual management of those patients undergoing SIRT. Blood samples were prospectively and consecutively taken from 49(More)
2D-3D registration for angiographic liver interventions is an unsolved problem mainly because of two reasons. First, a suitable protocol for Computed Tomography Angiography (CTA) to contrast liver arteries is not used in clinical practice. Second, an adequate registration algorithm which addresses the difficult task of aligning deformed vessel structures(More)
PURPOSE To evaluate the efficiency of a multimodality approach consisting of transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) as bridging therapy for patients with hepatocellular carcinoma (HCC) awaiting orthotopic liver transplantation (OLT) and to evaluate the histopathological response in explant specimens. MATERIALS(More)
This paper presents an adaptive visualization for helping the needle insertion task for RF liver ablation under CT-fluoroscopy (CT-fluoro) guidance. It shows slices of the 3D CT-volume that are resulting from the out-of-plane motion parameters along weighted isosurfaces in the convergence basin of the employed cost function. The visualization is coupled to(More)
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