Tobias A. Jenkins

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Vascular cell adhesion molecule-1 (VCAM-1) is expressed not only by cytokine-activated endothelium in the kidney, but also by nonvascular cells such as renal tubular epithelial cells (TEC) and mesangial cells (MC). VCAM-1 is upregulated in these cells by the cytokines TNF-alpha, IL-1, and IFN-gamma. We have examined herein the regulation of VCAM-1(More)
The angiotensin AT4 receptor was originally defined as the specific, high-affinity binding site for the hexapeptide angiotensin IV (Ang IV). Subsequently, the peptide LVV-hemorphin 7 was also demonstrated to be a bioactive ligand of the AT4 receptor. Central administration of Ang IV, its analogues or LVV-hemorphin 7 markedly enhance learning and memory in(More)
14 Rhamnolipids [RL] are heterogeneous glycolipid molecules that are composed of one or two 15 L-rhamnose sugars and one or two β-hydroxy fatty acids, which can vary in their length and 16 branch size. They are biosurfactants, predominantly produced by Pseudomonas aeruginosa 17 and are important virulence factors, playing a major role in P. aeruginosa(More)
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