Tjeerd Olde Scheper

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A mathematical model for the intracellular circadian rhythm generator has been studied, based on a negative feedback of protein products on the transcription rate of their genes. The study is an attempt at examining minimal but biologically realistic requirements for a negative molecular feedback loop involving considerably faster reactions, to produce(More)
A fundamental question in the field of circadian rhythms concerns the biochemical and molecular nature of the oscillator. There is strong evidence that circadian oscillators are cell autonomous and rely on periodic gene expression. In Drosophila, Neurospora, Aplysia, and vertebrates, circadian oscillators are thought to be based on molecular autoregulatory(More)
Chaos provides many interesting properties that can be used to achieve computational tasks. Such properties are sensitivity to initial conditions, space filling, control and synchronization. Chaotic neural models have been devised to exploit such properties. In this paper, a chaotic spiking neuron model is investigated experimentally. This investigation is(More)
The non-linear dynamics of a chaotic attractor offer a number of useful features to the developer of neuromorphic systems. Included in these is the ability for efficient memory storage and recall. A chaotic attractor has a potentially infinite number of Unstable Periodic Orbits (UPO) embedded within it. These orbits can be stabilised with the application of(More)
One of the mysteries surrounding the phenomenon of chaos is that it can rarely be found in biological systems. This has led to many discussions of the possible presence and interpretation of chaos in biological signals. It has caused empirical biologists to be very sceptical of models that have chaotic properties or even employ chaos for problem solving(More)