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  • Tiziana Bisogno, Lumír Ondřej Hanuš, +7 authors Vincenzo Di Marzo
  • Medicine, Chemistry
  • British journal of pharmacology
  • 2001 (First Publication: 1 October 2001)
  • 1. (-)-Cannabidiol (CBD) is a non-psychotropic component of Cannabis with possible therapeutic use as an anti-inflammatory drug. Little is known on the possible molecular targets of this compound. WeExpand
  • Susan M. Huang, Tiziana Bisogno, +12 authors Vincenzo Di Marzo
  • Medicine, Chemistry
  • Proceedings of the National Academy of Sciences…
  • 2002 (First Publication: 11 June 2002)
  • The vanilloid receptor VR1 is a nonselective cation channel that is most abundant in peripheral sensory fibers but also is found in several brain nuclei. VR1 is gated by protons, heat, and theExpand
  • Susan M. Huang, Tiziana Bisogno, +10 authors Joseph M. Walker
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2001 (First Publication: 16 November 2001)
  • In mammals, specific lipids and amino acids serve as crucial signaling molecules. In bacteria, conjugates of lipids and amino acids (referred to as lipoamino acids) have been identified and found toExpand
  • Luciano De Petrocellis, Alessia Ligresti, +5 authors Vincenzo Di Marzo
  • Medicine, Chemistry
  • British journal of pharmacology
  • 2011 (First Publication: 1 August 2011)
  • BACKGROUND AND PURPOSE Cannabidiol (CBD) and Δ(9) -tetrahydrocannabinol (THC) interact with transient receptor potential (TRP) channels and enzymes of the endocannabinoid system. EXPERIMENTALExpand
  • Tiziana Bisogno, Dominique J. Melck, +4 authors Vincenzo Di Marzo
  • Medicine, Chemistry
  • The Biochemical journal
  • 2000 (First Publication: 1 November 2000)
  • We reported previously that synthetic amides of polyunsaturated fatty acids with bioactive amines can result in substances that interact with proteins of the endogenous cannabinoid system (ECS). HereExpand
  • Sabatino Maione, Tiziana Bisogno, +7 authors Vincenzo di Marzo
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental…
  • 2006 (First Publication: 1 March 2006)
  • In the ventrolateral periaqueductal gray (PAG), activation of excitatory output neurons projecting monosynaptically to OFF cells in the rostral ventromedial medulla (RVM) causes antinociceptiveExpand