Titus Brown

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We present a new tierra-inspired artiicial life system with local interactions and two-dimensional geometry , based on an update mechanism akin to that of 2D cellular automata. We nd that the spatial geometry is conducive to the development of diversity and thus improves adaptive capabilities. We also demonstrate the adaptive strength of the system by(More)
(1992) Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation. The cell-centered database: a database for multiscale structural and protein localization data from light and electron microscopy. Neuroinformatics(More)
Using an artiicial system of self-replicating strings, we show a correlation between the age of a genotype and its abundance that reeects a punctuated rather than gradual picture of evolution, as suggested long ago by Willis. In support of this correlation, we measure genotype abundance distributions and nd universal coee-cients. Finally, we propose a(More)
Errors in scientific results due to software bugs are not limited to a few high-profile cases that lead to retractions and are widely reported. Here I estimate that in fact most scientific results are probably wrong if data have passed through a computer, and that these errors may remain largely undetected. The opportunities for both subtle and profound(More)
The discipline of Computational Anatomy focuses on shape analysis of anatomical structures obtained in biomedical imaging. Under the auspices of the Mouse Morphometry Biomedical Informatics Research Network (www.nbirn.net), a processing pipeline has been developed to enable processing of morphometry data obtained from the Cell Centered DataBase. As a(More)
Lampreys are extant representatives of the jawless vertebrate lineage that diverged from jawed vertebrates around 500 million years ago. Lamprey genomes contain information crucial for understanding the evolution of gene families in vertebrates. The ATP-binding cassette (ABC) gene family is found from prokaryotes to eukaryotes. The recent availability of(More)
(University gold medal for achieving the highest grade among all branches of engineering) PROFESSOR, Michigan State University RESEARCH AREAS 1. Big Data and Cloud Computing: (a) Genome sequence analysis in the Cloud. (a) Genome sequence based identification for security systems (b) Indexing and querying Genome Sequence Databases (c) Fast Algorithms for(More)
We introduce a method for visualizing evolutionary activity of genotypes. Following a proposal of Bedau and Packard 13], we deene a genotype's evolutionary activity in terms of the history of its concentration in the evolving population. To visualize this evolutionary activity we graph the distribution of evolutionary activity in the population of genotypes(More)
We introduce a method for visualizing evolutionary activity of genotypes. Following a proposal of Bedau and Packard 11], we deene a genotype's evolutionary activity in terms of the history of its concentration in the evolving population. To visualize this evolutionary activity we graph the distribution of evolutionary activity in the population of genotypes(More)
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