Titin Andri Wihastuti

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Vasa vasorum anti-angiogenesis through H 2 O 2 , HiF-1α, nF-κB, and inOs inhibition by mangosteen pericarp ethanolic extract (Garcinia mangostana linn) in hypercholesterol-diet-given Rattus norvegicus Wistar strain Titin andri Wihastuti
BACKGROUND Oxidative stress in atherosclerosis produces H2O2 and triggers the activation of nuclear factor kappa beta (NF-κB) and increase of inducible nitric oxide synthase (iNOS). The formation of vasa vasorum occurs in atherosclerosis. Vasa vasorum angiogenesis is mediated by VEGFR-1 and upregulated by hypoxia-inducible factor-1α (HIF-1α). The newly(More)
This research aims to find out the levels of xanthone in mangosteen pericarp extract (MPE) and to prove the ability of xanthone in modulating the activity of paraoxonase-1 (PON-1), reduce oxidized-low density lipoprotein (ox-LDL) and increase the levels of acetylcholinesterase (AChE) serum in animal model with organophosphat subchronic and subcutaneous(More)
AIM to detect the levels of CEC and expression of NFκB in the three groups of subjects with certain conditions. METHODS this study is an exploratory study using human peripheral blood samples. The study subjects comprised three groups, the group of 23 healthy people, a group of 35 people that has one or more risk factors for vascular disease and a group(More)
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