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d) mice were from Taconic. Batf −/− mice on 129S6/SvEv, C57BL/6, and BALB/c background were used. Batf −/− mice on a 129S6/SvEv background were previously generated 2. Batf −/− mice were backcrossed five generation to the C57BL/6 background and eight generation to the BALB/c background. Aicda −/− mice were obtained from T. Honjo had reviewed and approved(More)
Researches around wireless sensor network (WSN) were very prolific recently. However, traffic modeling related WSN research was poorly less. In this paper, source traffic dynamics in a simulated target tracking WSN scenario are explored. We find the source traffic arrival process doesn't follow the usually considered Poisson model. Instead, an ON/OFF model(More)
Scheduling algorithms play an important role for TDMA-based wireless sensor networks. Existing TDMA scheduling algorithms address a multitude of objectives. However, their adaptation to the dynamics of a realistic wireless sensor network has not been investigated in a satisfactory manner. This is a key issue considering the challenges within industrial(More)
The primary cilium, which disassembles before mitotic entry and reassembles after mitosis, organizes many signal transduction pathways that are crucial for cell life and individual development. However, how ciliogenesis is regulated during the cell cycle remains largely unknown. Here we show that GSK3β, Dzip1, and Rab8 co-regulate ciliogenesis by promoting(More)
Activation-induced cytidine deaminase (AID) initiates immunoglobulin (Ig) heavy-chain (IgH) class switch recombination (CSR) and Ig variable region somatic hypermutation (SHM) in B lymphocytes by deaminating cytidines on template and nontemplate strands of transcribed DNA substrates. However, the mechanism of AID access to the template DNA strand,(More)
Neuroinflammation mediated by activation of microglia and interruption of the blood-brain barrier (BBB) is an important factor that contributes to neuron death and infarct area diffusion in ischemia reperfusion injury. Finding novel molecules to regulate neuroinflammation is of significant clinical value. We have previously shown that adjudin, a small(More)
Remote ischemic perconditioning (RIPer) has been proved to provide potent cardioprotection. However, there are few studies on neuroprotection of RIPer. This study aims to clarify the neuroprotective effect of RIPer and the role of autophagy induced by RIPer against cerebral ischemia reperfusion injury in rats. Using a transient middle cerebral artery(More)
We report results of a megabase-scale phylogenomic analysis of the Reptilia, the sister group of mammals. Large-scale end-sequence scanning of genomic clones of a turtle, alligator, and lizard reveals diverse, mammal-like landscapes of retroelements and simple sequence repeats (SSRs) not found in the chicken. Several global genomic traits, including(More)