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d) mice were from Taconic. Batf −/− mice on 129S6/SvEv, C57BL/6, and BALB/c background were used. Batf −/− mice on a 129S6/SvEv background were previously generated 2. Batf −/− mice were backcrossed five generation to the C57BL/6 background and eight generation to the BALB/c background. Aicda −/− mice were obtained from T. Honjo had reviewed and approved(More)
The increasing use of nanotechnology in consumer products and medical applications underlies the importance of understanding its potential toxic effects to people and the environment. Although both fullerene and carbon nanotubes have been demonstrated to accumulate to cytotoxic levels within organs of various animal models and cell types and carbon(More)
Scheduling algorithms play an important role for TDMA-based wireless sensor networks. Existing TDMA scheduling algorithms address a multitude of objectives. However, their adaptation to the dynamics of a realistic wireless sensor network has not been investigated in a satisfactory manner. This is a key issue considering the challenges within industrial(More)
We report results of a megabase-scale phylogenomic analysis of the Reptilia, the sister group of mammals. Large-scale end-sequence scanning of genomic clones of a turtle, alligator, and lizard reveals diverse, mammal-like landscapes of retroelements and simple sequence repeats (SSRs) not found in the chicken. Several global genomic traits, including(More)
  • Uttiya Basu, Fei-Long Meng, Celia Keim, Veronika Grinstein, Evangelos Pefanis, Jennifer Eccleston +9 others
  • 2011
Activation-induced cytidine deaminase (AID) initiates immunoglobulin (Ig) heavy-chain (IgH) class switch recombination (CSR) and Ig variable region somatic hypermutation (SHM) in B lymphocytes by deaminating cytidines on template and nontemplate strands of transcribed DNA substrates. However, the mechanism of AID access to the template DNA strand,(More)