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Ribbon Synapse Plasticity in the Cochleae of Guinea Pigs after Noise-Induced Silent Damage

• Lijuan Shi, Lijie Liu, +4 authors Jian Wang
• PloS one
• 2013

Noise exposure at low levels or low doses can damage hair cell afferent ribbon synapses without causing permanent threshold shifts. In contrast to reports in the mouse cochleae, initial damage to… (More)

Silent Damage of Noise on Cochlear Afferent Innervation in Guinea Pigs and the Impact on Temporal Processing

• Lijie Liu, Hui Wang, +6 authors Jian Wang
• PloS one
• 2012

Noise-exposure at levels low enough to avoid a permanent threshold shift has been found to cause a massive, delayed degeneration of spiral ganglion neurons (SGNs) in mouse cochleae. Damage to the… (More)

A Meta-Analysis of Oxidative Stress Markers in Depression

• Tao Liu, Shuming Zhong, +5 authors Xiang Yang Zhang
• PloS one
• 2015

OBJECT Studies have suggested that depression was accompanied by oxidative stress dysregulation, including abnormal total antioxidant capacity (TAC), antioxidants, free radicals, oxidative damage and… (More)

Altered neuronal activity in the primary motor cortex and globus pallidus after dopamine depletion in rats

• Min Wang, Min Li, Xiwen Geng, Zhimin Song, Tingting He
• Journal of the Neurological Sciences
• 2015

The involvement of dopamine (DA) neuron loss in the etiology of Parkinson's disease has been well documented. The neural mechanisms underlying the effects of DA loss and the resultant motor… (More)

Noise induced hearing loss impairs spatial learning/memory and hippocampal neurogenesis in mice

• Lijie Liu, Pei Shen, +8 authors Jian Wang
• Scientific reports
• 2016

Hearing loss has been associated with cognitive decline in the elderly and is considered to be an independent risk factor for dementia. One of the most common causes for acquired sensorineural… (More)

Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation

• Yiliang Xu, Yuhui Sun, +8 authors Qi Xu
• Cell Discovery
• 2015

Genetic variations in the human dysbindin-1 gene (DTNBP1) have been associated with schizophrenia. As a result of alternative splicing, the human DTNBP1 gene generates at least three distinct protein… (More)

Hippocampal Mechanisms Underlying Impairment in Spatial Learning Long After Establishment of Noise-Induced Hearing Loss in CBA Mice

• Lijie Liu, Chuanying Xuan, +7 authors Jian Wang
• Front. Syst. Neurosci.
• 2018

Sensorineural hearing loss (SNHL) has been demonstrated in many clinical reports as a risk factor that promotes the development of cognitive impairment. However, the underlying neurological… (More)

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