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BACKGROUND Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is the etiologic agent of KS, the most common AIDS-related malignancy. The majority of KS tumor cells harbor latent KSHV virus but only a small percentage undergoes spontaneous lytic replication. Viral reactivation from latency is crucial for the pathogenesis and development of KS, but the(More)
OBJECTIVES To investigate whether a single dose of dexmedetomidine (DEX) improves surgical field visibility. STUDY DESIGN Randomized, prospective, double-blind study. SETTING Tertiary teaching hospital. INTERVENTIONS ASA I or II patients undergoing tympanoplasty with ossiculoplasty were randomly assigned to receive either 0.8 μg/kg DEX (Group D) or(More)
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