• Publications
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Effects and mechanism of downregulation of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells
The survivin protein, a member of the inhibitors of apoptosis (IAP) family, has gained popularity as a therapeutic target for cancer due to its selective expression in tumor cells and its significantExpand
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Tripchlorolide induces autophagy in lung cancer cells by inhibiting the PI3K/AKT/mTOR pathway and improves cisplatin sensitivity in A549/DDP cells.
Tripchlorolide (T4) has been shown to induce A549 lung cancer cell death predominantly by activating an autophagy pathway. However, the underlying mechanism remains unclear. Herein, we demonstratedExpand
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Clinicopathological significance of oestrogen receptor expression in non-small cell lung cancer
Objective To investigate the expression and clinicopathological significance of the oestrogen receptor (ER) in non-small cell lung cancer (NSCLC). Methods ER expression was examined byExpand
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Survivin expression in human lung cancer and the influence of its downregulation on the biological behavior of human lung cancer cells.
The aim of the present study was to detect the expression of survivin in human lung cancer and to investigate the influence of its downregulation on the biological behavior of A549 lung cancer cells.Expand
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Therapeutic effects of sorafenib on the A549/DDP human lung adenocarcinoma cell line in vitro.
The aim of the present study was to observe the effects of sorafenib on the proliferation, apoptosis and invasion of A549/DDP cisplatin-resistant lung adenocarcinoma cells cultured in vitro. TheExpand
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[Clinical features of 127 cases of novel influenza A (H1N1) infection in Fujian Province].
  • Y. Chen, H. Weng, +7 authors W. Chen
  • Medicine
  • Zhonghua jie he he hu xi za zhi = Zhonghua jiehe…
  • 1 February 2010
OBJECTIVE to investigate the clinical features of 127 cases of the novel influenza A/H1N1 infection in Fujian Province. METHODS this study included 127 human cases with the novel influenza A/H1N1Expand
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Effect and mechanism of miR-146a on malignant biological behaviors of lung adenocarcinoma cell line
The aim of the present study was to assess the expression of microRNA-146a (miR-146a) in human lung adenocarcinoma cells, its effect on cellular behaviors, and the underlying molecular mechanisms.Expand
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Interleukin-18 suppresses angiogenesis and lymphangiogenesis in implanted Lewis lung cancer
ObjectiveTo investigate the effects of interleukin-18 (IL-18) on implanted Lewis lung cancer in suppressing angiogenesis and lymphangiogenesis.MethodsOne week after hypodermic inoculation of LewisExpand
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[Effects of interleukin-18 on asthmatic airway inflammation: experimental study of guinea pig asthmatic model].
OBJECTIVE To investigate the effects of Interleukin-18 (IL-18) on asthmatic airway inflammation. METHODS Thirty healthy adult male guinea pigs were randomly divided into 3 equal groups: asthmaticExpand
Tripchlorolide induces autophagy in lung cancer cells by inhibiting the PI3K/AKT/mTOR pathway and improves cisplatin sensitivity in A549/DDP cells
Tripchlorolide (T4) has been shown to induce A549 lung cancer cell death predominantly by activating an autophagy pathway. However, the underlying mechanism remains unclear. Herein, we demonstratedExpand
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