Ting Zhou

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A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts.

Ronghui Li, Jialiang Liang, +21 authors Duanqing Pei
Cell stem cell
2010

Epithelial-to-mesenchymal transition (EMT) is a developmental process important for cell fate determination. Fibroblasts, a product of EMT, can be reset into induced pluripotent stem cells (iPSCs)… (More)

Generation of human induced pluripotent stem cells from urine samples

Ting Zhou, Christina Benda, +13 authors Miguel A Esteban
Nature Protocols
2012

Human induced pluripotent stem cells (iPSCs) have been generated with varied efficiencies from multiple tissues. Yet, acquiring donor cells is, in most instances, an invasive procedure that requires… (More)

Genome-Wide Survey and Developmental Expression Mapping of Zebrafish SET Domain-Containing Genes

Xiao-Jian Sun, Peng-fei Xu, +9 authors Zhu Chen
PloS one
2008

SET domain-containing proteins represent an evolutionarily conserved family of epigenetic regulators, which are responsible for most histone lysine methylation. Since some of these genes have been… (More)

Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation.

Nan Chen, Wenfeng Fang, +10 authors Li Zhang
Journal of thoracic oncology : official…
2015

INTRODUCTION Epidermal growth factor receptor (EGFR) mutation status was reported to be associated with programmed death-ligand 1 (PD-L1) expression. However, the molecular mechanism of PD-L1… (More)

Glycyrrhizin protects brain against ischemia-reperfusion injury in mice through HMGB1-TLR4-IL-17A signaling pathway.

Jiancheng Zhang, Yan Wu, Zelin Weng, Ting Zhou, Tao Feng, Yun Lian Lin
Brain research
2014

High mobility group box 1 (HMGB1)-Toll-like receptor 4 (TLR4) signaling has been recently found to induce interleukin (IL)-17A secretion in drug-induced hepatitis and myocardial I/R injury. The… (More)

Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

Allison E Mayle, Liubin Yang, +8 authors Margaret A. Goodell
Blood
2015

DNA methyltransferase 3A (DNMT3A) is mutated in hematologic malignancies affecting myeloid, mixed, and lymphoid lineages, and these mutations are associated with poor prognosis. Past studies in mice… (More)

The Missense of Smell: Functional Variability in the Human Odorant Receptor Repertoire

Joel D Mainland, Andreas Keller, +11 authors Hiroaki Matsunami
Nature Neuroscience
2014

Humans have ∼400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how… (More)

EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

Wenfeng Fang, Jianwei Zhang, +21 authors Li Zhang
Oncotarget
2014

PD-L1 expression is a feature of Epstein-Barr virus (EBV) associated malignancies such as nasopharyngeal carcinoma (NPC). Here, we found that EBV-induced latent membrane protein 1 (LMP1) and IFN-γ… (More)

New Asian types of Varroa destructor: a potential new threat for world apiculture

Maria Navajas, Denis L. Anderson, +4 authors Yves Le Conte
Apidologie
2011

The invasion of the Western honey bee, Apis mellifera, by Varroa destructor is attributed to two mitochondrial haplotypes (K and J) that shifted last century from their primary host the Eastern honey… (More)

Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?

Ting Zhou, Paul Hasty, Christi A. Walter, Alexander J R Bishop, Linda M Scott, Vivienne I. Rebel
Experimental hematology
2013

Myelodysplastic syndrome (MDS) is considered a hematopoietic stem cell disease that is characterized by abnormal hematopoietic differentiation and a high propensity to develop acute myeloid leukemia.… (More)

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