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BACKGROUND This study aims to investigate the clinical features of invasive community-acquired Staphylococcus aureus (CA-SA) infection in Chinese children and analyze its molecular features. METHODS Clinical data and invasive CA-SA isolates were prospectively collected. Pediatric risk of mortality (PRISM) score was used for disease severity measurement.(More)
The effect of environmental temperature on neuronal spiking behaviours is investigated by numerically simulating the temperature dependence of spiking threshold of the Hodgkin-Huxley neuron subject to synaptic stimulus. We find that the spiking threshold exhibits a global minimum in a " comfortable temperature " range where spike initiation needs weakest(More)
Cucurbitacin B (CuB), a triterpenoid compound isolated from the stems of Cucumis melo, has long been used to treat hepatitis and hepatoma in China. Although its remarkable anti-cancer activities have been reported, the mechanism by which it achieves this therapeutic activity remains unclear. This study was designed to investigate the molecular mechanisms by(More)
Autism spectrum disorders (ASDs) are a group of mental illnesses highly correlated with gut microbiota. Recent studies have shown that some abnormal aromatic metabolites in autism patients are presumably derived from overgrown Clostridium species in gut, which may be used for diagnostic purposes. In this paper, a GC/MS based metabolomic approach was(More)
The resistance distance r G (u, v) between two vertices u, v of a connected graph G is defined as the effective resistance between them in the corresponding electrical network constructed from G by replacing each edge of G with a unit resistor. Let G be a connected graph, the degree resistance distance of G is defined as D R (G) = {u,v}⊆V (G) [d(u) +(More)
We present a distributed academic search and mining system? AMiner-mini. The system offers intra- and inter- university level academic search and mining services. It integrates academic data from multiple sources and performs disambiguation for people names, which is a fundamental issue for searching people. We employ a two-phases approach that formalizes(More)