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It has been reported previously that diabetic cardiomyopathy can be inhibited or reverted with chronic zinc supplementation. In the current study, we hypothesized that total cardiac calcium and zinc content is altered in early onset diabetes mellitus characterized in part as hyperglycemia (HG) and that exposure of zinc ion (Zn2+) to isolated cardiomyocytes(More)
In recent years, natural disasters and environmental pollution events occur frequently and seriously threaten people's lives and property. The first step of disaster prevention and mitigation is obtaining the monitoring data of disaster situation. Currently, there are two main problems in transferring monitoring data, one is that disaster monitoring sensors(More)
There is an urgent need for an efficient approach to obtain a large-scale and renewable source of functional human vascular smooth muscle cells (VSMCs) to establish robust, patient-specific tissue model systems for studying the pathogenesis of vascular disease, and for developing novel therapeutic interventions. Here, we have derived a large quantity of(More)
An ultra-low power analog front end is presented to capture ExG (including ECG, EEG and EMG) signals. It consists of a capacitively coupled chopper instrument amplifier, a chopping spike filter and a VGA. Implemented in standard 0.35&#x03BC;m CMOS technology, this analog front end occupying 0.54 mm<sup>2</sup> chip area, while consuming only 3.96&#x03BC;A(More)
To meet the requirement of multi-channel healthcare applications, a second order incremental &#x03A3;&#x0394; ADC in 0.35&#x03BC;m CMOS technology is proposed for minimizing power consumption and achieving high resolution. The ADC achieves 95dB dynamic range in 240Hz bandwidth. The total power consumption of the ADC is 80&#x03BC;W and the chip core area is(More)
Salivary biomarkers have been increasingly popular in stress research as saliva is easily produced and collection is non-invasive and not limited by geographical distance or lack of infrastructure. Several salivary biomarkers have been utilized in stress research, for instance, salivary cortisol, salivary amylase and salivary immunoglobulin A. Despite being(More)
This paper presents an energy-efficient reconfigurable 3<sup>rd</sup>-order continuous-time &#931;&#916; modulator, which can satisfy multi-band modes for 4G-LTE application. To expand the reconfigurable bandwidth range and optimize the energy efficiency, this work employs a flexible architecture, which can switch between feed-forward and feed-back(More)