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An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Combining two complementary computational strategies for conservation-based motif discovery improves the ability to identify the specificity of transcriptional regulators from genome-wide chromatin immunoprecipitation data. Expand
The UCSC Genome Browser Database: update 2009
The UCSC Genome Browser Database (GBD, http://genome.ucsc.edu) is a publicly available collection of genome assembly sequence data and integrated annotations for a large number of organisms, including extensive comparative-genomic resources. Expand
Combining phylogenetic data with co-regulated genes to identify regulatory motifs
We introduce a new algorithm called PhyloCon (Phylogenetic Consensus) that takes into account both conservation among orthologous genes and co-regulation of genes within a species. Expand
TextBugger: Generating Adversarial Text Against Real-world Applications
We present TextBugger, a general attack framework for generating adversarial texts and demonstrate its effectiveness, evasiveness, and efficiency. Expand
Kernel Sparse Representation-Based Classifier
Sparse representation-based classifier (SRC), a combined result of machine learning and compressed sensing, shows its good classification performance on face image data. Expand
Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection.
  • Y. Loo, D. Owen, +15 authors M. Gale
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 11 April 2006
Viral signaling through retinoic acid-inducible gene-I (RIG-I) and its adaptor protein, IFN promoter-stimulator 1 (IPS-1), activates IFN regulatory factor-3 (IRF-3) and the host IFN-alpha/betaExpand
101.7-Tb/s (370×294-Gb/s) PDM-128QAM-OFDM transmission over 3×55-km SSMF using pilot-based phase noise mitigation
Record capacity transmission of 101.7-Tb/s (370×294-Gb/s) is performed over 3×55 km SSMF using PDM-128QAM-OFDM modulation and pilot-based phase noise mitigation. Achieved spectral efficiency of 11Expand
Hepatitis C Virus Core Protein Inhibits Mitochondrial Electron Transport and Increases Reactive Oxygen Species (ROS) Production*
Hepatitis C infection causes a state of chronic oxidative stress, which may contribute to fibrosis and carcinogenesis in the liver. Previous studies have shown that expression of the HCV core proteinExpand
ENCODE whole-genome data in the UCSC Genome Browser
The Encyclopedia of DNA Elements (ENCODE) project is an international consortium of investigators funded to analyze the human genome with the goal of producing a comprehensive catalog of functional elements. Expand
Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53
The evolutionary forces that establish and hone target gene networks of transcription factors are largely unknown. Transposition of retroelements may play a role, but its global importance, beyond aExpand