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Serology characteristics of SARS-CoV-2 infection since exposure and post symptom onset
TLDR
Serology testing provides an important complement to RNA testing in the later stages of illness for pathogenic-specific diagnosis and helpful information to evaluate the adapted immunity status of patients. Expand
Toxoplasma gondii: protective effect of an intranasal SAG1 and MIC4 DNA vaccine in mice.
TLDR
These vaccines were able to elicit a significant humoral and cellular immune response in vaccinated mice and they can increase survival rate and prolong the life of mice that were infected by T. gondii especially in the pcDNA3.1-SAG1-MIC4 group. Expand
Major parasitic diseases of poverty in mainland China: perspectives for better control
TLDR
The prevalence rates, geographical distributions, epidemic characteristics, risk factors, and clinical manifestations of parasitic diseases of poverty listed in the first issue of the journal Infectious Diseases of Poverty on 25 October 2012 are reviewed. Expand
[Rare blood group B (A) detection and safe transfusion].
TLDR
It is concluded that the forward ABO serological grouping and reverse ABOSerological grouping are not compatible, that may be verified by family survey and molecular biological methods. Expand
[Serologic and molecular biological detection of rare B(A) blood group].
TLDR
It is concluded that the sample inconsistent between the group typing and reverse typing could be typed by molecular biological method, and the molecular basis of weak expression of ABO blood group is elucidated. Expand
Rapid and Visual Detection of Trichinella Spp. Using a Lateral Flow Strip-Based Recombinase Polymerase Amplification (LF-RPA) Assay
TLDR
The developed LF-RPA assay is presented as a new simple, specific, sensitive, rapid and convenient method for the detection of Trichinella infection in domestic animals. Expand
Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities, and Perspectives.
TLDR
An overview of the current understanding of the host immune response to T. gondii infection is provided and the key limitations for the development of an effective, safe, and durable toxoplasmosis vaccine are summarized. Expand
Immunization with Toxoplasma gondii GRA17 Deletion Mutant Induces Partial Protection and Survival in Challenged Mice
TLDR
It is shown that immunization with ΔGRA17 strain evokes cell-mediated and neutralizing antibody responses and confers some degree of protection against challenge with homologous and heterologous virulent T. gondii strains. Expand
Evaluation of the basic functions of six calcium-dependent protein kinases in Toxoplasma gondii using CRISPR-Cas9 system
TLDR
The results indicated that there was no significant difference between the six KO-CDPK strains and wild-type strain in virulence and the lytic cycle including invasion, egress, and replication, suggesting that the six CDPKs may participate in other functions in T. gondii. Expand
Live Attenuated Pru: &Dgr;cdpk2 Strain of Toxoplasma gondii Protects Against Acute, Chronic, and Congenital Toxoplasmosis
TLDR
The use of T. gondii Pru:Δcdpk2 mutant strain represents a promising approach to protection against acute, chronic, and congenital toxoplasmosis in mice. Expand
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