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BACKGROUND Higher eukaryotes express a diverse population of messenger RNAs generated by alternative splicing. Large-scale methods for monitoring gene expression must adapt in order to accurately detect the transcript variation generated by this splicing. RESULTS We have designed a high-density oligonucleotide microarray with probesets for more than one(More)
permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Tissue-specific exon discovery <p>Comprehensive exon microarrays with a simple intra-gene normalization algorithm were used to detect human tissue-specific alternative splicing events, suggesting significant expression outside of known exons(More)
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