Learn More
BACKGROUND Despite the widespread use of paracetamol for many years, the analgesic serum concentrations of paracetamol are unknown. Therefore the correlation between serum paracetamol concentrations and the analgesic effect was studied. METHODS Sixty-four women undergoing laparoscopic sterilization were included in a double-blind, placebo-controlled,(More)
The aim of this analysis was to examine the cost-effectiveness of Contreet Foam (A) in comparison with three other commonly used venous leg ulcer treatment protocols: Aquacel Ag (B), Actisorb Silver (C) and Iodoflex (D). A health-economic analysis reflecting the UK treatment practice and cost structure was performed. The analysis was set up to assess the(More)
BACKGROUND The primary purpose of the study was to examine the absorption of acetaminophen by measuring serum and saliva concentrations produced by a standard postoperative acetaminophen dosing regimen and secondary to examine the correlation between saliva and serum concentrations of acetaminophen after rectal and oral dosing. METHODS Twenty-four women,(More)
This study evaluated the safety and clinical performance of Alione hydrocapillary adhesive dressing, Coloplast A/S, a newly developed moist wound healing dressing designed for exudate management of heavily to lightly exuding ulcers. Twelve patients with heavily to moderately exuding chronic venous leg ulcers were assessed during a 4-week observation period.(More)
Twenty-three children (aged between 9 weeks and 11 yr) were given paracetamol suppositories 25 mg kg-1 every 6 h (maximum 5 days) after major surgery and serum and saliva concentrations were measured. There was a good correlation (r = 0.91, P < 0.05) between saliva and serum concentrations. A one-compartment linear model with first-order elimination and(More)
  • 1