Timothy Snell

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UNLABELLED For opioid-tolerant patients, conventional patient-controlled analgesia dosing may be ineffective. We present a cardiac surgery patient with a history of significant opioid tolerance and prior episodes of severe postoperative pain. Using the patient's response to a large-dose fentanyl infusion in conjunction with a pharmacokinetic simulation,(More)
Embedded electrical systems for passenger vehicles are highly complex distributed systems with varying system boundaries. The surge towards further electrification of vehicles demands the deployment of high voltage systems that provide propulsion through an electric motor as part of a hybrid electric or pure electric drive train. This demands additional(More)
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