Timothy Seers

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miRNAs play critical roles in various biological processes by targeting specific mRNAs. Current approaches to identifying miRNA targets are insufficient for elucidation of a miRNA regulatory network. Here, we created a cell-based screening system using a luciferase reporter library composed of 4,891 full-length cDNAs, each of which was integrated into the(More)
This report describes a case of hepatocellular carcinoma (HCC) in an adolescent with perinatally acquired HIV and HBV co-infection, arising despite more than a decade of suppressive antiretroviral therapy for both HIV and HBV. This case raises important questions regarding optimal HCC screening in this high-risk group and the oncogenic potential of even(More)
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