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Production of the antimalarial drug precursor artemisinic acid in engineered yeast
Malaria is a global health problem that threatens 300–500 million people and kills more than one million people annually. Disease control is hampered by the occurrence of multi-drug-resistant strainsExpand
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Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels.
The ability to generate microorganisms that can produce biofuels similar to petroleum-based transportation fuels would allow the use of existing engines and infrastructure and would save an enormousExpand
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Design and Construction of a Double Inversion Recombination Switch for Heritable Sequential Genetic Memory
Background Inversion recombination elements present unique opportunities for computing and information encoding in biological systems. They provide distinct binary states that are encoded into theExpand
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Design, implementation and practice of JBEI-ICE: an open source biological part registry platform and tools
The Joint BioEnergy Institute Inventory of Composable Elements (JBEI-ICEs) is an open source registry platform for managing information about biological parts. It is capable of recording informationExpand
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A tightly regulated inducible expression system utilizing the fim inversion recombination switch.
The fim inversion system of Escherichia coli (E. coli) can behave as a unidirectional switch in an efficient manner. We have developed a new expression system for E. coli, comprising theExpand
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DeviceEditor visual biological CAD canvas
BackgroundBiological Computer Aided Design (bioCAD) assists the de novo design and selection of existing genetic components to achieve a desired biological activity, as part of an integratedExpand
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Title: Synthetic Biology Open Language (SBOL) Version 1.0.0
The Fuels Synthesis Division of the Joint BioEnergy Institute (JBEI)
Author(s): Baidoo, Edward E.; Beller, Harry R.; Chan, Rossana; Chhabra, Swapnil; Chou, Howard; Dahl, R.; Dmytriv, Z.; Dunlop, Mary J.; Fortman, C.; Garcia, David E.; Martin, Hector Garcia; Gilmore,Expand