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  • Pu Xia, Toyoshi Inoguchi, Timothy S Kern, Ronald L. Engerman, Peter J Oates, George L King
  • Medicine, Biology
  • Diabetes
  • 1994 (First Publication: 1 September 1994)
  • Similar vascular pathological conditions are observed in diabetic animals and those with diet-induced hypergalactosemia. Both diabetes and hypergalactosemia are believed to cause vascular dysfunctionContinue Reading
  • Mariana G Rosca, T Mustaţă, +6 authors Miriam F. Weiss
  • Medicine, Biology
  • American journal of physiology. Renal physiology
  • 2005 (First Publication: 1 August 2005)
  • Chronic hyperglycemia causes structural alterations of proteins through the Maillard reaction. In diabetes, methylglyoxal (MGO)-induced hydroimidazolones are the predominant modification. In contrastContinue Reading
  • Remya Robinson, Veluchamy Amutha Barathi, Shyam S Chaurasia, Tien Y Wong, Timothy S Kern
  • Medicine, Biology
  • Disease Models & Mechanisms
  • 2012 (First Publication: 1 July 2012)
  • Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and one of the major causes of blindness worldwide. The pathogenesis of DR has been investigated using severalContinue Reading