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Initiating a regenerative response; cellular and molecular features of wound healing in the cnidarian Nematostella vectensis
BackgroundWound healing is the first stage of a series of cellular events that are necessary to initiate a regenerative response. Defective wound healing can block regeneration even in animals with aExpand
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The evolutionary diversification of LSF and Grainyhead transcription factors preceded the radiation of basal animal lineages
BackgroundThe transcription factors of the LSF/Grainyhead (GRH) family are characterized by the possession of a distinctive DNA-binding domain that bears no clear relationship to other knownExpand
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Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation
Hox gene transcription factors are important regulators of positional identity along the anterior–posterior axis in bilaterian animals. Cnidarians (e.g., sea anemones, corals, and hydroids) are theExpand
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Coral comparative genomics reveal expanded Hox cluster in the cnidarian-bilaterian ancestor.
The key developmental role of the Hox cluster of genes was established prior to the last common ancestor of protostomes and deuterostomes and the subsequent evolution of this cluster has played aExpand
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The Precambrian emergence of animal life: a geobiological perspective
The earliest record of animals (Metazoa) consists of trace and body fossils restricted to the last 35 Myr of the Precambrian. It has been proposed that animals arose much earlier and underwentExpand
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“Dorsal–Ventral” Genes Are Part of an Ancient Axial Patterning System: Evidence from Trichoplax adhaerens (Placozoa)
Abstract Placozoa are a morphologically simplistic group of marine animals found globally in tropical and subtropical environments. They consist of two named species, Trichoplax adhaerens and moreExpand
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The radial expression of dorsal-ventral patterning genes in placozoans, Trichoplax adhaerens, argues for an oral-aboral axis
The placozoans are a morphologically simplistic group of marine animals found globally in tropical and subtropical environments. They consist of a single named species, Trichoplax adhaerens and haveExpand
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Nodal signaling is required for mesodermal and ventral but not for dorsal fates in the indirect developing hemichordate, Ptychodera flava
ABSTRACT Nodal signaling plays crucial roles in vertebrate developmental processes such as endoderm and mesoderm formation, and axial patterning events along the anteroposterior, dorsoventral andExpand
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Functional studies on the role of Notch signaling in Hydractinia development.
The function of Notch signaling was previously studied in two cnidarians, Hydra and Nematostella, representing the lineages Hydrozoa and Anthozoa, respectively. Using pharmacological inhibition inExpand
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In vivo imaging of Nematostella vectensis embryogenesis and late development using fluorescent probes
BackgroundCnidarians are the closest living relatives to bilaterians and have been instrumental to studying the evolution of bilaterian properties. The cnidarian model, Nematostella vectensis, is aExpand
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