Timothy Lyerla

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Hermansky Pudlak syndrome (HPS) is a heterogeneous recessive genetic disease with a tendency to develop lung fibrosis with aging. A mouse strain with two mutant HPS genes affecting separate vesicle trafficking pathways, C57BL/6-Hps1 ep -Ap3b1 pe , exhibits severe lung abnormalities at young ages, including enlarged alveolar type II (ATII) cells with giant(More)
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