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  • Timothy Hla, K Neilson
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1992 (First Publication: 15 August 1992)
  • Cyclooxygenase (Cox), also known as prostaglandin (PG) H synthase (EC, catalyzes the rate-limiting step in the formation of inflammatory PGs. A major regulatory step in PG biosynthesis isExpand
  • Myat Lin Oo, Shobha Thangada, +5 authors Timothy Hla
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2007 (First Publication: 23 March 2007)
  • Sphingosine 1-phosphate (S1P), a multifunctional lipid mediator, regulates lymphocyte trafficking, vascular permeability, and angiogenesis by activation of the S1P1 receptor. This receptor isExpand