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OBJECTIVE The authors performed a prospective evaluation of staging laparoscopy with laparoscopic ultrasonography in predicting surgical resectability in patients with carcinomas of the pancreatic head and periampullary region. SUMMARY BACKGROUND DATA Pancreatic resection with curative intent is possible in a select minority of patients who have(More)
OBJECTIVE To identify risk factors associated with cancer-specific survival and develop a predictive model for patients undergoing primary hepatic resection for metastatic colorectal cancer. BACKGROUND No published studies investigated collectively the inter-relation of factors related to patient cancer-specific survival after hepatectomy for metastatic(More)
Neoadjuvant chemotherapy (NC) can improve the resectability of hepatic colorectal metastases (CRM). However, there is concern regarding its impact on operative risk. We reviewed 750 consecutive liver resections performed for CRM in a single unit (1996-2005) to evaluate whether NC affected morbidity and mortality. Redo hepatic resections or patients(More)
INTRODUCTION The safety and efficacy of liver resection for colorectal and neuroendocrine liver metastases is well established. However, there is lack of consensus regarding long-term effectiveness of hepatic resection for non-colorectal, non-neuroendocrine (NCNN) liver metastases. METHODS A review of prospectively collected data of patients undergoing(More)
BACKGROUND The aim of the present study was to determine whether raised pre-operative serum creatinine increased the risk of renal failure after liver resection. METHOD Data were studied from 1535 consecutive liver resections. Outcomes in patients with pre-operative creatinine </=124 micromol/l (Group 1) were compared with those with pre-operative(More)
  • Timothy G. John, Andrew Wright, +4 authors O. James Garden
  • 1999
A prospective study was performed comparing laparoscopy with laparoscopic ultrasonography (LapUS), transabdominal ultrasonography (USS), computed tomography (CT), and selective visceral angiography with portal phase venography (SVA) for the assessment of resectability in 50 patients with pancreatic or periampullary cancer. The results were stratified by TNM(More)
Seeding of tumour in the needle track following percutaneous needle biopsy of liver neoplasms is rarely reported. We describe two such cases following the needle biopsy of an hepatocellular carcinoma and secondary colorectal carcinoma respectively. The risk of needle track recurrence of liver tumours should not be regarded as insignificant. The diagnosis of(More)
OBJECTIVE To investigate the impact of preoperative transjugular intrahepatic portosystemic stent-shunt (TIPSS) on patients undergoing liver transplantation. DESIGN A retrospective non-randomized comparative clinical study. SETTING Tertiary referral institution. PATIENTS, PARTICIPANTS Twenty-four patients with liver cirrhosis, portal hypertension and(More)
BACKGROUND The management of patients with recurrent colorectal liver metastases (RCLM) remains controversial. This study aimed to determine whether repeat liver resection for RCLM could be performed with acceptable morbidity, mortality and long-term survival. METHODS Of 1121 consecutive liver resections performed and prospectively analysed between 1987(More)
OBJECTIVE The authors describe the technique of staging laparoscopy with laparoscopic contact ultrasonography in the preoperative assessment of patients with liver tumors, and assess its impact on the selection of patients for hepatic resection with curative intent. SUMMARY BACKGROUND DATA Laparoscopy may be useful in the selection of patients with a(More)