Timothy E. Chupp

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The feasibility of brain MRI with laser-polarized 129Xe in a small animal model is demonstrated. Naturally abundant 129Xe is polarized and introduced into the lungs of Sprague-Dawley rats. Polarized xenon gas dissolves in the blood and is transported to the brain where it accumulates in brain tissue. Spectroscopic studies reveal a single, dominant,(More)
The neutron longitudinal and transverse asymmetries A n 1 and A n 2 have been extracted from deep inelas-tic scattering of polarized electrons by a polarized 3 He target at incident energies of 19.42, 22.66 and 25.51 GeV. The measurement allows for the determination of the neutron spin structure functions g n 1 (x; Q 2) and g n 2 (x; Q 2) over the range(More)
K. Abe , T. Akagi , B. D. Anderson , P. L. Anthony , R. G. Arnold , T. Averett , H. R. Band , C. M. Berisso , P. Bogorad , H. Borel , P. E. Bosted , V. Breton , M. J. Buenerd , G. D. Cates , T. E. Chupp , S. Churchwell , K. P. Coulter , M. Daoudi , P. Decowski , R. Erickson , J. N. Fellbaum , H. Fonvieille , R. Gearhart , V. Ghazikhanian , K. A. Griffioen ,(More)
  • M Sharma, E Babcock, +14 authors W S Wilburn
  • Physical review letters
  • 2008
We have observed depolarization effects when high intensity cold neutron beams are incident on alkali-metal spin-exchange-polarized 3He cells used as neutron spin filters. This was first observed as a reduction of the maximum attainable 3He polarization and was attributed to a decrease of alkali-metal polarization, which led us to directly measure(More)
The first magnetic resonance imaging studies of laser-polarized (129)Xe, dissolved in the blood and tissue of the lungs and the heart of Sprague-Dawley rats, are described. (129)Xe resonances at 0, 192, 199, and 210 ppm were observed and assigned to xenon in gas, fat, tissue, and blood, respectively. One-dimensional chemical-shift imaging (CSI) reveals(More)
A perfusion phantom with unique features and a wide variety of applications in MR and other imaging modalities is presented. Using microfabrication technique, a network of microchannels, in the scale of actual microvasculature, was created. The geometry of the network was determined based on Murrays minimum work law to simulate the hemodynamic in actual(More)
K. Abe,21 T. Akagi,18,21 B. D. Anderson,7 P. L. Anthony,18 R. G. Arnold,1 T. Averett,5 H. R. Band,23 C. M. Berisso,9 P. Bogorad,15 H. Borel,6 P. E. Bosted,1 V. Breton,3 M. J. Buenerd,18 G. D. Cates,15 T. E. Chupp,10 S. Churchwell,9 K. P. Coulter,10 M. Daoudi,18 P. Decowski,17 R. Erickson,18 J. N. Fellbaum,1 H. Fonvieille,3 R. Gearhart,18 V. Ghazikhanian,8(More)