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  • Timothy Curtis Hallstrom, W Scott Moye-Rowley
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2000 (First Publication: 1 December 2000)
  • Multiple or pleiotropic drug resistance most often occurs in Saccharomyces cerevisiae due to substitution mutations within the Cys6-Zn(II) transcription factors Pdr1p and Pdr3p. These dominantContinue Reading
  • David J. Katzmann, Timothy Curtis Hallstrom, Yannick Mahé, W Scott Moye-Rowley
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 1996 (First Publication: 20 September 1996)
  • Saccharomyces cerevisiae has large number of genes that can be genetically altered to produce a multiple or pleiotropic drug resistance phenotype. The homologous zinc finger transcription factorsContinue Reading
  • David J. Katzmann, Timothy Curtis Hallstrom, +4 authors W. Scott Moye-Rowley
  • Biology, Medicine
  • Molecular and cellular biology
  • 1995 (First Publication: 1 December 1995)
  • Semidominant mutations in the PDR1 or PDR3 gene lead to elevated resistance to cycloheximide and oligomycin. PDR1 and PDR3 have been demonstrated to encode zinc cluster transcription factors.Continue Reading
  • Timothy Curtis Hallstrom, David J. Katzmann, R. J. Torres, W J Sharp, W. Scott Moye-Rowley
  • Medicine, Biology
  • Molecular and Cellular Biology
  • 1998 (First Publication: 1 March 1998)
  • ABSTRACT Multiple or pleiotropic drug resistance in the yeastSaccharomyces cerevisiae requires the expression of several ATP binding cassette transporter-encoding genes under the control of the zincContinue Reading
  • Laura R. Bohrer, Shuai Chen, Timothy Curtis Hallstrom, Haojie Huang
  • Biology, Medicine
  • Endocrinology
  • 2010 (First Publication: 1 November 2010)
  • Androgens and the androgen receptor are important for both normal prostate development and progression of prostate cancer (PCa). However, the underlying mechanisms are not fully understood. TheContinue Reading
  • Esther P. Black, Timothy Curtis Hallstrom, Holly Dressman, Mike West, Joseph R. Nevins
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2005 (First Publication: 1 November 2005)
  • The E2F family of transcription factors provides essential activities for coordinating the control of cellular proliferation and cell fate. Both E2F1 and E2F3 proteins have been shown to beContinue Reading
  • Xiaoting Zhang, Ania Kolaczkowska, +4 authors W Scott Moye-Rowley
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2005 (First Publication: 28 January 2005)
  • Saccharomyces cerevisiae cells that have lost their mitochondrial genome (ρ0) strongly induce transcription of multidrug resistance genes, including the ATP-binding cassette transporter gene PDR5.Continue Reading