Timo Schirmer

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PURPOSE To compare lumbar muscle fat-signal fractions derived from three-dimensional dual gradient-echo magnetic resonance (MR) imaging and multiple gradient-echo MR imaging with fractions from single-voxel MR spectroscopy in patients with low back pain. MATERIALS AND METHODS This prospective study had institutional review board approval, and written(More)
This comparative study of tumour patients and volunteers aimed at differentiating liver parenchyma from neoplastic lesions by using localised 1H MRS at 3.0 T as an adjunct to MRI. In total 186 single-voxel proton spectra of the liver were acquired at 3.0 T using the body transmit receive coil. Consecutive stacks of breath-hold spectra were acquired in the(More)
Proton magnetic resonance spectroscopy (1H-MRS) provides specific metabolic information not otherwise observable by any other imaging method. 1H-MRS of the brain at 3 T is a new tool in the modern neuroradiological armamentarium whose main advantages, with respect to the well-established and technologically advanced 1.5-T 1H-MRS, include a higher(More)
Magnetic resonance imaging (MRI) allows excellent tissue characterization in the area of the petroclival region and can depict lesions not visualized with ultrasound or computed tomography (CT). The aim of this study was to demonstrate the clinical feasibility and utility of an interactive MR-guidance system to target and biopsy tumors in the petroclival(More)
Minimally-invasive, laser-induced interstitial thermotherapy (LITT) of solid tumors represents a valid alternative to surgical procedures such as tumor resections. Within the framework of a palliative study on 16 patients, a total of 25 metastases in the liver were treated in an open MR system (0.5 T). The intraoperative scanner design allows patient-based(More)
OBJECTIVE The purpose of our study was to show how, despite pathognomonic signs of cerebral involvement in chronic progressive external ophthalmoplegia (CPEO), mitochondrial respiratory chain insufficiency is associated with increased lactate and reduced N-acetylaspartate. CPEO and mitochondrial myopathy are caused by mitochondrial DNA mutations leading to(More)
s der a n g e n o m m e n e n Poster Hoehaufl6sende F-MRT-Untersuchungen mit ,,dual phased array"-Spulen D. Auer, G. K. Elbel, T. Schirmer, R. A. Jones MPI fa Psychiatrie, K[iaisches lnstitut, Ma Ziel dieser Studie war eine Verbesserung der Ortsaufl6sung funktioneller MR-Untersuchungen (F-MRT) durch Anwendung geeigneter Oberfl~ichenspulen. An bisher 12(More)
BACKGROUND Inner volume (IV) excitation was explored with respect to scan time reduction of cardiac gated double inversion recovery multi-echo fast spin echo (MEFSE) to measure the transverse relaxation time (T2 ) in the myocardium. METHODS The IV imaging was achieved by applying orthogonal slice selection for the excitation and refocusing pulses. The T2(More)
PURPOSE Magnetic resonance stereoscopic imaging (MRSI) of the prostate is an emerging technique that may enhance targeting and assessment in radiotherapy. Current practices in radiotherapy invariably involve image guidance. Gold seed fiducial markers are often used to perform daily prostate localization. If MRSI is to be used in targeting prostate cancer(More)
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