Timo Mustonen

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BACKGROUND The pathophysiological mechanisms of impaired perfusion during acute subarachnoid haemorrhage (SAH) are incompletely understood. Cerebral perfusion at the micro vascular level can be assessed by single photon emission computed tomography (SPECT). We used a SPECT approach with 99mTc-ECD to measure the cerebral perfusion heterogeneity and(More)
Offshoring (offshore outsourcing) is increasingly used in software-centric projects, specifically in the development phases of software projects. Using a mixture of onsite local staff and remote offshore staff in business-centric projects, such as business consulting, requirements elicitation and software testing, put many challenges to team organizing,(More)
PURPOSE To prospectively evaluate whether subarachnoid hemorrhage (SAH) is associated with a change in the apparent diffusion coefficient (ADC) in normal-appearing brain parenchyma. MATERIALS AND METHODS Institutional review board approval and informed consent were obtained for all patient and volunteer studies. One hundred patients (48 men, 52 women;(More)
BACKGROUND AND PURPOSE Aneurysmal subarachnoid haemorrhage (aSAH) can be associated with acute global and regional decrease in cerebral perfusion. Furthermore, cerebral vasospasm may lead to development of delayed ischaemic deficits. The aim of the study was to find out whether cerebral perfusion heterogeneity, an indicator of cerebral microvascular(More)
BACKGROUND In many centers, (18)F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is used to monitor treatment response after definitive (chemo)radiotherapy [(C)RT] for head and neck squamous cell carcinoma (HNSCC), but its usefulness remains somewhat controversial. We aimed at assessing the accuracy of FDG-PET/CT in(More)
BACKGROUND Translational researchers need robust IT solutions to access a range of data types, varying from public data sets to pseudonymised patient information with restricted access, provided on a case by case basis. The reason for this complication is that managing access policies to sensitive human data must consider issues of data confidentiality,(More)
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