Learn More
Multiple sclerosis (MS) is associated with significant economic burden and high rates of unemployment. This investigation evaluated patient and disease characteristics associated with work loss and work initiation using the NARCOMS patient registry. Patient and disease characteristics associated with transitions to unemployment or employment were evaluated(More)
Despite important advances in the treatment of multiple sclerosis (MS) over recent years, the introduction of several disease-modifying therapies (DMTs), the burden of progressive disability and premature mortality associated with the condition remains substantial. This burden, together with the high healthcare and societal costs associated with MS, creates(More)
OBJECTIVE To assess the safety, tolerability and pharmacokinetics of an interleukin (IL)-12/23 monoclonal antibody (mAb) in subjects with a relapsing form of multiple sclerosis (MS). METHODS A phase I, double-blind, placebo-controlled, sequential dose escalation study was conducted in 20 subjects with MS. Subjects were randomized (4:1) to receive a single(More)
BACKGROUND AND OBJECTIVE In this study the effectiveness of an outpatient education program for adult asthmatics (AFAS) was evaluated in a controlled and randomized trial over a period of 6 months. PATIENTS AND METHODS In a randomized controlled study 78 educated patients with mild to moderate asthma (mean age 48.6 years) and 42 equally treated but(More)
  • 1