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Mild citrullinemia is an allelic variant of classical citrullinemia type I also caused by deficiency of the urea cycle enzyme argininosuccinate synthetase (ASS). Affected patients comprise a biochemical but no clinical phenotype. However, there is no reliable parameter allowing conclusions regarding the course of the disorder or its type of manifestation.(More)
Paroxetine (Paxil) is a selective serotonin reuptake inhibitor, one of a new class of antidepressants used in the treatment of obsessive-compulsive disorder, panic disorder, and depression. Paroxetine potentiates serotonergic activity through the selective inhibition of serotonin reuptake in the central nervous system. There are few reported overdoses in(More)
Image optimization, feature extraction and classification in Neurobiology: "Dendritic spines under stress" Abstract In neurons, the dendritic structure is sensitive to changes in the environment. Several treatments have been known to create changes in dendritic structure. 3D confocal images have been used before to evaluate and quantify changes in dendritic(More)
This paper develops a new explanation for user satisfaction with IS. Combining insights from expectation (dis)confirmation theory (ECT) and importance-performance analysis (IPA), we focus on the gaps between the importance of particular IS attributes, and the performance of a system on those attributes, as an explanation for user satisfaction. We identify(More)
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