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Direct solution methods for optimal control problems treat them from the perspective of global optimization: perform a global search for the control function that optimizes the required objective. Increasingly, Differential Evolution is being recognized as a powerful global optimizer for optimal control. A parameterization technique is required, which can(More)
In many disease models, the dynamics are described by a system of differential equations. When the spread of the disease is controlled by a treatment strategy, an obvious challenge is to find the best treatment possible. Mathematically, this problem is known as optimal control, or dynamic optimization. To solve these problems, researchers are increasingly(More)
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