Tim Leong

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BACKGROUND The results of management of seminoma of the testis at the Department of Radiation Oncology St Vincent's Hospital, Sydney were evaluated retrospectively to: (i) establish that outcomes were in keeping with published results from centres in Australia and overseas; (ii) assess the impact of chemotherapy on management; and (iii) to determine 'best(More)
INTRODUCTION Mortality of patients on extracorporeal membrane oxygenation (ECMO) remains high. The objectives of this study were to assess the factors associated with outcome of patients undergoing ECMO in a large ECMO referral centre and to compare veno-arterial ECMO (VA ECMO) with veno-venous ECMO (VV ECMO). METHODS We reviewed a prospectively obtained(More)
A large outbreak of infection and colonization with multiple genera of gram-negative bacilli carrying the metallo- beta -lactamase gene bla(IMP-4) occurred in a 36-bed intensive care unit at a tertiary hospital in Australia. The organisms emerged rapidly, caused severe infections, and contributed to mortality. Controlling the spread of these organisms(More)
OBJECTIVES To analyze infectious complications that occur in patients who receive extracorporeal membrane oxygenation (ECMO), associated risk factors, and consequences on patient outcome. DESIGN Retrospective observational survey from 2005 through 2011. PARTICIPANTS AND SETTING Patients who required ECMO in an Australian referral center. METHODS Cases(More)
The use of alternative medicines is increasing and poorly regulated. We describe a case of severe cyanide poisoning arising from amygdalin, a putative vitamin supplement. A 32-year-old woman arrived in the emergency department by ambulance unresponsive, shocked and with fixed dilated pupils. She was hypothermic and tachycardic but was breathing(More)
BACKGROUND Psoriasis is a hyperproliferative, cutaneous disorder with the potential to lower levels of folate. This may result in raised levels of homocysteine, an independent risk factor for the development of cardiovascular disease. OBJECTIVE A study was conducted to compare levels of red-cell folate (RCF) and homocysteine in patients with psoriasis and(More)
A multimodal hospital-wide central line-associated bloodstream infection (CLABSI) risk reduction strategy was implemented over a 20-month period at an Australian center. Reduced CLABSI rates were observed in both intensive care units (ICUs) (incidence rate ratio [IRR], 0.39; P < .001) and non-ICU wards (IRR, 0.54; P < .001). The median time to CLABSI onset(More)
BACKGROUND Screen designs in computerized clinical information systems (CIS) have been modeled on their paper predecessors. However, limited understanding about how paper forms support clinical work means that we risk repeating old mistakes and creating new opportunities for error and inefficiency as illustrated by problems associated with computerized(More)
The incidence of shunt nephritis has decreased over the past several years due to the increased use of ventriculoperitoneal (VP) shunts rather than the ventriculovascular systems for which this complication was originally reported in 1965. Despite this trend, the syndrome has been reported in cases of VP shunting and, for this reason, merit a renewed look.(More)