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The dust-jacket aptly sums up this study by Sir Henry Harris, Emeritus Regius Professor of Medicine and former Head of the Sir William Dunn School of Pathology at Oxford, as "the first scholarly history of research on the genetics of somatic cells". This is an interesting, elegantly presented, and certainly detailed, account of what might be called the flip(More)
Carbon particles and isotopic quail grafts were used as markers to study the salient features of the fate map of the chick forelimb between stages 20 and 27. The grafting technique confirmed the reliability of the carbon method: they both revealed striking asymmetries in which apical mesodermal tissue was progressively displaced in a proximal direction (as(More)
The pathways of selected optic axons were traced in representative urodele, anuran, teleost, reptile, and avian species by filling the fibers with HRP or by tracing, at the light and electron microscopic (EM) level, the degeneration caused by focal retinal or optic nerve lesions. In all species it was shown that fibers retain retinotopic neighborhood(More)
The formation of the branches of the optic tract has been studied with the use of [3H]proline autoradiography, during development and during regeneration of the optic nerve in Xenopus with one compound ventral (VV) eye made by the embryonic fusion of two ventral eye fragments. The formation of the optic pathway was abnormal in that the lateral branch failed(More)
Observations in a wide selection of lower vertebrate embryos have confirmed classical descriptions concerning segmentation of the early head mesoderm. The premandibular (PM) segment is seen as the most rostral representative of a continuous rostro-caudal series of condensations in the paraxial mesoderm, luminisations within which are secondary and variable(More)
1. The reorganization of the retinotectal projection which results after partial ablation of tectal tissue was examined in goldfish using electrophysiological methods. 2. Regardless of the size of a unilateral ablation of caudal tectum, an orderly and virtually complete, 'compressed', visual projection re-formed on the remaining tectum after crushing the(More)