Tim J B Crayford

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OBJECTIVE To assess whether a measure of uterine blood flow impedance (the pulsatility index, PI) as determined by transvaginal ultrasonography with color blood flow imaging, may be used to assess endometrial receptivity immediately before the time of embryo transfer (ET) after assisted conception. DESIGN A prospective study of infertile women who had(More)
OBJECTIVE To investigate the relationship between estradiol (E2), progestogen, and impedance to blood flow in the uterine artery. SUBJECTS Twelve postmenopausal women treated for two cycles with transdermal E2, 0.05 mg/d, with either norethindrone acetate, 0.7 mg, or medroxyprogesterone acetate, 10 mg added sequentially. MEASUREMENTS Transvaginal(More)
OBJECTIVE To estimate the prevalence of medically unexplained symptoms in patients who most frequently attend outpatient services. DESIGN Retrospective cohort study over three years with review of case notes. SETTING Secondary care services in the South Thames (West) NHS region. PARTICIPANTS Outpatient attenders with new appointments in 1993. MAIN(More)
BACKGROUND Medically unexplained physical symptoms present one of the most common problems in modern medical practice but often prove difficult to manage. The central position of the GP in the care of patients with medically unexplained symptoms has been emphasized repeatedly, but little is known about the attitudes of GPs to this role. Understanding how(More)
BACKGROUND Frequent attenders in medical settings account for a disproportionate amount of health-care resources. Little is known about service use and costs of secondary care in those frequent attenders presenting with medically unexplained symptoms. AIMS To compare health-care use and costs of patients with medically unexplained symptoms with other(More)
The aim of this study was to investigate the interrater reliability of the recognition of medically unexplained symptoms by medical investigators. The casenotes of 56 consecutive secondary care out-patient attenders were examined by three medical investigators. The investigators determined whether the presenting symptoms were medically unexplained (not,(More)
BACKGROUND There are few longitudinal studies of patients with medically unexplained symptoms. The aim of this study was to investigate outcome in frequent attenders in secondary care who present repeatedly with medically unexplained symptoms. METHOD Forty-eight patients presenting with medically unexplained symptoms, from a sample of 61, participated in(More)
The current study explored distress and adjustment over time and a woman's ability to find benefit in her experience of breast cancer. Over 700 women were initially assessed at a pre-diagnostic visit to a breast clinic. Of those who were originally diagnosed, 39 women participated in all four study assessments, completed over a two-and-one-half-year period(More)
OBJECTIVE To examine mortality in members of the two UK Houses of Parliament compared with the general population, 1945-2011. DESIGN Retrospective cohort analysis of death rates and predictors of mortality in Members of Parliament (MPs) and members of the House of Lords (Lords). SETTING UK. PARTICIPANTS 4950 MPs and Lords first joining the UK(More)