• Publications
  • Influence
BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams
BackgroundIn many genomics projects, numerous lists containing biological identifiers are produced. Often it is useful to see the overlap between different lists, enabling researchers to quicklyExpand
  • 876
  • 42
  • PDF
Benchmarking ortholog identification methods using functional genomics data
BackgroundThe transfer of functional annotations from model organism proteins to human proteins is one of the main applications of comparative genomics. Various methods are used to analyzeExpand
  • 176
  • 24
  • PDF
Identification of novel functional TBP‐binding sites and general factor repertoires
Our current knowledge of the general factor requirement in transcription by the three mammalian RNA polymerases is based on a small number of model promoters. Here, we present a comprehensiveExpand
  • 114
  • 4
Evolution of closely linked gene pairs in vertebrate genomes.
The orientation of closely linked genes in mammalian genomes is not random: there are more head-to-head (h2h) gene pairs than expected. To understand the origin of this enrichment in h2h gene pairs,Expand
  • 16
  • 2
Testing statistical significance scores of sequence comparison methods with structure similarity
TLDR
Sequence comparison algorithm with both e-value and Z-score statistics is evaluated, using ROC, CVE and AP measures. Expand
  • 18
  • 2
PhyloPat: an updated version of the phylogenetic pattern database contains gene neighborhood
TLDR
We present an updated version of PhyloPat which allows the complete Ensembl gene database to be queried using phylogenetic patterns. Expand
  • 10
  • 2
  • PDF
From Big Data to Precision Medicine
TLDR
For over a decade the term “Big data” has been used to describe the rapid increase in volume, variety and velocity of information available, not just in medical research but in almost every aspect of our lives. Expand
  • 97
  • 1
Heavier‐than‐air flying machines are impossible
TLDR
We summarize what we think are the (im)possibilities of modelling GPCRs using the coordinates of bovine rhodopsin as a template. Expand
  • 56
  • 1
PhyloPat: phylogenetic pattern analysis of eukaryotic genes
TLDR
We present a tool named PhyloPat which allows the complete Ensembl gene database to be queried using phylogenetic patterns. Expand
  • 18
  • 1
  • PDF
...
1
2
3
...