Tiffany Y Kim

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Enzyme replacement therapy has been successful in alleviating morbidity and improving endurance in Mucopolysaccharidosis (MPS) type I, II, and VI, however little attention has been paid to the effects on bone mineralization. Brief case reports in MPS type III and IV suggest that bone mineral density (BMD) is diminished, but did not account for patient size.(More)
The mucopolysaccharidoses (MPS) are a common cause of carpal tunnel syndrome (CTS) in children and adolescents. As the MPS diseases are progressive in nature, it is essential that CTS in these children is readily diagnosed and treated, before damage to the median nerve becomes irreversible. Currently, no standards for diagnosing and treating CTS associated(More)
OBJECTIVE Although the use of oral cholecystographic agents (OCAs) had declined due to limited availability, there is literature to suggest it is an effective medication for thyrotoxicosis in appropriate clinical situations. METHODS The authors performed a PubMed search and systematically reviewed all the English written case reports, original studies and(More)
Invited Commentary Variability in DXAReporting andOther Challenges in Osteoporosis Evaluation A 65-year-old woman undergoes routine screening dualenergy x-ray absorptiometry (DXA),which reveals T scores of −2.3 at the femoral neck, −2.7 at theWard triangle, −2.2 at the total hip, and −1.9 at the posteroanterior (PA) lumbar spine. Evaluation reveals no(More)
Bone marrow fat is a unique fat depot that may regulate bone metabolism. Marrow fat is increased in states of low bone mass, severe underweight, and diabetes. However, longitudinal effects of weight loss and improved glucose homeostasis on marrow fat are unclear, as is the relationship between marrow fat and bone mineral density (BMD) changes. We(More)
METHODS A number of 41 pt with 45 lesions were successfully treated by FFR-guided DCB-only PCI and underwent 6-month angiographic and OCT f/u. OCT analysis included manual tracing of dissections and plaques, which were entered into a dedicated software program. The algorithm enabled beyond the spread-out vessel reconstruction (Fig. 1) also the computation(More)
PURPOSE OF REVIEW This study aims to describe bone marrow fat changes in diabetes and to discuss the potential role of marrow fat in skeletal fragility. RECENT FINDINGS Advances in non-invasive imaging have facilitated marrow fat research in humans. In contrast to animal studies which clearly demonstrate higher levels of marrow fat in diabetes, human(More)
OBJECTIVES Using intravascular ultrasound (IVUS), the authors compared outcomes by observed wire position (intraplaque vs. subintimal) achieved during successful chronic total occlusion (CTO) lesion treatment. BACKGROUND Recent successes in CTO percutaneous coronary intervention (PCI) have used both intraluminal and subintimal wire tracking to improve(More)
Cause of an Elevated Lactate Level To theEditorAnarticle in theDiagnosticTest Interpretation series discussed elevated lactate levels in a non–critically ill patient.1 We wish to underscore the importance of considering infection as a cause of lactic acidosis early in the clinical course of similar patients. Infection is one of the leading causes of death(More)