Tiffany Tang

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—Memory corruption attacks continue to be a major vector of attack for compromising modern systems. Numerous defenses have been proposed against memory corruption attacks, but they all have their limitations and weaknesses. Stronger defenses such as complete memory safety for legacy languages (C/C++) incur a large overhead, while weaker ones such as(More)
—Memory corruption attacks continue to be a major vector of attack for compromising modern systems. Numerous defenses have been proposed against memory corruption attacks, but they all have their limitations and weaknesses. Stronger defenses such as complete memory safety for legacy languages (C/C++) incur a large overhead, while weaker ones such as(More)
The classification of T-cell and natural-killer- (NK-) cell lymphomas has been updated in the 4th edition of the World Health Organization (WHO) classification of tumors of the haematopoietic and lymphoid tissue published in 2008. Based on recent epidemiological studies, NK-cell lymphomas occur almost exclusively in Asia and South America, although T-cell(More)
OBJECTIVE This study aims to compare the cost-effectiveness of various strategies of myeloid growth factor prophylaxis for reducing the risk of febrile neutropenia (FN) in patients with non-Hodgkin lymphoma in Singapore who are undergoing R-CHOP chemotherapy with curative intent. METHODS A Markov model was created to compare seven prophylaxis strategies:(More)
The majority of prostate cancer (PCa) deaths occur due to the metastatic spread of tumor cells to distant organs. Currently, there is a lack of effective therapies once tumor cells have spread outside the prostate. It is therefore imperative to rapidly develop therapeutics to inhibit the metastatic spread of tumor cells. Gain of cell motility and invasive(More)
Refractory and/or relapsed diffuse large B cell lymphoma (RR-DLBCL) patients are incurable with conventional chemotherapy due to the aggressiveness and the chemorefractory state of these tumors. DNA hypermethylation and histone deacetylation are two major epigenetic modifications by which aggressive DLBCL maintain their oncogenic state. We have previously(More)
BACKGROUND Von Hippel-Lindau (VHL) syndrome is a dominantly inherited multisystem cancer syndrome caused by a heterozygous mutation in the VHL tumor suppressor gene. Previous studies suggested that similar populations of Caucasian and Japanese patients have similar genotype or phenotype characteristics. In this comprehensive study of East Asian patients, we(More)
In this thesis, we argue that software-based defenses to code reuse attacks are fundamentally flawed. With code pointer integrity as a case study, we show that a secure and efficient software-based defense to code reuse attacks is impossible and thus motivate the case for hardware approaches. We then propose our tagged architecture system Taxi (Tagged C) as(More)
Second lymphoid neoplasms are an uncommon but recognized feature of non-Hodgkin's lymphomas, putatively arising secondary to common genetic or environmental risk factors. Previous limited evaluations of clonal relatedness between successive mature B-cell malignancies have yielded mixed results. We describe the case of a man with intravascular large B-cell(More)
Unusual sites of metastases are recognized in patients with renal cell carcinoma (RCC). However, the prognostic implications of these sites are not well understood. We used the Memorial Sloan-Kettering Cancer Center (MSKCC) risk classification for metastatic RCC to evaluate 912 consecutive patients with RCC managed at the Singapore General Hospital between(More)
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