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- Publications
- Influence
Diversity-oriented synthesis of macrocyclic peptidomimetics
- Albert Isidro-Llobet, Tiffanie Murillo, +6 authors D. Spring
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences
- 7 March 2011
Structurally diverse libraries of novel small molecules represent important sources of biologically active agents. In this paper we report the development of a diversity-oriented synthesis strategy… Expand
Synthesis of a stereochemically diverse library of medium-sized lactams and sultams via S(N)Ar cycloetherification.
- Baudouin Gerard, J. R. Duvall, +4 authors L. A. Marcaurelle
- Chemistry, Medicine
- ACS combinatorial science
- 11 July 2011
We have implemented an aldol-based "build/couple/pair" (B/C/P) strategy for the synthesis of stereochemically diverse 8-membered lactam and sultam scaffolds via S(N)Ar cycloetherification. Each… Expand
Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.
- Baudouin Gerard, M. Lee, +15 authors L. A. Marcaurelle
- Chemistry, Medicine
- The Journal of organic chemistry
- 21 May 2013
A diversity-oriented synthesis (DOS) strategy was developed for the synthesis of stereochemically diverse fused-ring systems containing a pyran moiety. Each scaffold contains an amine and methyl… Expand
Diversity-oriented synthesis of macrocyclic
- Tiffanie Murillo, P. Belló, +5 authors D. Spring
- Chemistry
- 2011