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The cadherins are a family of cell surface glycoproteins responsible for cell adhesion which play an important role in cell morphology, contact inhibition and signal transduction during tumorigenesis. Protocadherin 8 (PCDH8), a member of the cadherin family, has been reported to act as a tumor suppressor involved(More)
In a recent clinical observation, the growth of endothelial tumors, such as nasopharyngeal carcinoma, was repressed by the non-selective-adrenergic antagonist propranolol. In this study, we evaluated whether β-adrenoceptors (β-ARs), nuclear factor κB (NF-κB), vascular endothelial growth factor (VEGF), cyclooxygenase-2 (COX-2), matrix metalloproteinase-2(More)
Neoadjuvant chemotherapy has become prevalent in breast cancer therapies. Our previous research has reported that overexpression of miR-663 was associated with chemoresistance in breast cancer cells by targeting Heparin Sulfate Proteoglycan 2 (HSPG2). This study focused on exploring the potential role of miR-663 as a novel biomarker for chemotherapy in(More)
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