Tien-Hsiung Ku

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BACKGROUND Appropriate postoperative pain management contributes to earlier mobilization, shorter hospitalization, and reduced cost. The under treatment of pain may impede short-term recovery and have a detrimental long-term effect on health. This study focuses on Patient Controlled Analgesia (PCA), which is a delivery system for pain medication. This study(More)
Among 75218 splicing sites, 137 colon cancer specific alternative splicing isoforms were found by mining EST database. Alternative splicing database were first constructed by aligning EST to genomic sequence. Numbers of ESTs from normal or cancer colon tissue supporting splicing isoform at each splicing site were then queried and analyzed with Fisher exact(More)
Recently, pain management has become an important aspect of medical care. Patient Controlled Analgesia (PCA) is a particularly effective and flexible treatment that allows patients to adjust the dosages of the analgesics that control their pain after surgery. However, PCA requires manual operation for sustained attention, and should be analysed with other(More)
Unlike previous research on patient controlled analgesia, this study explores patient demand behavior over time. We apply clustering methods to disclose demand patterns among patients over the first 24h of analgesic medication after surgery. We consider demographic, biomedical, and surgery-related data in statistical analyses to determine predictors for(More)
Personal digital assistants (PDA) are increasingly being used in many medical fields. The object of this study is to introduce how the hospital computerization and the utilization of PDA can help to reduce the time of data processing for Acute Pain Service. After this study completed, we found that the use of PDA can dramatically reduce the time of data(More)
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