Identification and analysis of an interleukin 8-like molecule in rainbow trout Oncorhynchus mykiss.
- K. Laing, J. Zou, C. Secombes
- BiologyDevelopmental and Comparative Immunology
- 1 June 2002
Characterization of three novel beta-defensin antimicrobial peptides in rainbow trout (Oncorhynchus mykiss).
- E. Casadei, Tiehui Wang, J. Zou, Jose L González Vecino, S. Wadsworth, C. Secombes
- BiologyMolecular Immunology
- 1 October 2009
Immune gene expression profiling of Proliferative Kidney Disease in rainbow trout Oncorhynchus mykiss reveals a dominance of anti-inflammatory, antibody and T helper cell-like activities
- B. Gorgoglione, Tiehui Wang, C. Secombes, J. Holland
- BiologyVeterinary Research
- 16 July 2013
This work, for the first time, suggests that PKD pathogenesis is shaped by an anti-inflammatory phenotype, a profound B cell / antibody response and dysregulated TH cell-like activities.
Cloning and Characterization of Rainbow Trout Interleukin-17A/F2 (IL-17A/F2) and IL-17 Receptor A: Expression during Infection and Bioactivity of Recombinant IL-17A/F2
- M. Monte, Tiehui Wang, J. Holland, J. Zou, C. Secombes
- BiologyInfection and Immunity
- 12 November 2012
ABSTRACT Lower vertebrates have been found to possess genes that have similar homology to both interleukin (IL)-17A and IL-17F, which have been termed IL-17A/F. In fish species, several of these…
Cloning, expression analysis and bioactivity studies of rainbow trout (Oncorhynchus mykiss) interleukin-22.
- M. Monte, J. Zou, Tiehui Wang, A. Carrington, C. Secombes
- BiologyCytokine
- 1 July 2011
The innate and adaptive immune system of fish
- C. Secombes, Tiehui Wang
- Biology
- 2012
Abstract: This chapter describes what is known about the main components and responses of the innate and adaptive immune system of fish. The chapter first reviews the organs, cells and molecules of…
The cytokine networks of adaptive immunity in fish.
- Tiehui Wang, C. Secombes
- BiologyFish and Shellfish Immunology
- 1 December 2013
The First Cytokine Sequence Within Cartilaginous Fish: IL-1β in the Small Spotted Catshark (Scyliorhinus canicula)1
- S. Bird, Tiehui Wang, J. Zou, C. Cunningham, C. Secombes
- BiologyJournal of Immunology
- 1 April 2002
The cloning of IL-1β in S. canicula, the first cytokine sequenced within cartilaginous fish, verifies previous bioactivity evidence for the presence of inflammatory cytokines.
Cloning and expression of the first nonmammalian interleukin‐11 gene in rainbow trout Oncorhynchus mykiss
- Tiehui Wang, J. Holland, N. Bols, C. Secombes
- BiologyThe FEBS Journal
- 1 March 2005
The expression results suggest that fish IL‐11 is an active player in the cytokine network and the host immune response to infection, and is widely distributed and modulated by infection and other cytokines.
Molecular cloning and characterization of interferon regulatory factors 4 and 8 (IRF-4 and IRF-8) in rainbow trout, Oncorhynchus mykiss.
- J. Holland, Asma Karim, S. Bird
- BiologyFish and Shellfish Immunology
- 1 July 2010
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