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  • Tibor Kristian, Bo K. Siesjö
  • Medicine
  • Stroke
  • 1998 (First Published: 1 March 1998)
  • BACKGROUND This review article deals with the role of calcium in ischemic cell death. A calcium-related mechanism was proposed more than two decades ago to explain cell necrosis incurred in cardiacContinue Reading
  • Aaron Long, Katrina Owens, Anna E Schlappal, Tibor Kristian, Paul S. Fishman, Rosemary A. Schuh
  • Medicine
  • BMC Neurology
  • 2015 (First Published: 1 December 2015)
  • BackgroundMitochondrial dysfunction is a hallmark of neurodegenerative diseases including Alzheimer’s disease (AD), with morphological and functional abnormalities limiting the electron transportContinue Reading
  • Krish Chandrasekaran, Julie L. Hazelton, Yuchuan Wang, Gary Fiskum, Tibor Kristian
  • Medicine, Biology
  • The Journal of neuroscience : the official…
  • 2006 (First Published: 20 December 2006)
  • Mitochondrial dysfunction contributes to the pathophysiology of both acute and chronic neurodegenerative disorders. Quantification of mitochondrial bioenergetic properties generally requires the useContinue Reading
  • Tibor Kristian, Irene B. Hopkins, Mary C McKenna, Gary Fiskum
  • Medicine, Biology
  • Journal of Neuroscience Methods
  • 2006 (First Published: 1 April 2006)
  • To study neurons or glia-specific mitochondria one needs to isolate these organelles from primary neuronal or astrocytic cell culture. This work provides novel method for isolation of functional andContinue Reading
  • Hiroyuki Uchino, Reiko Minamikawa-Tachino, Tibor Kristian, Guy A Perkins, Futoshi Shibasaki
  • Biology, Medicine
  • Neurobiology of Disease
  • 2002 (First Published: 1 August 2002)
  • Transient global or forebrain ischemia leads to severe brain damage following delayed neuronal cell death. We previously reported that cyclosporin A (CsA) provides near total suppression of brainContinue Reading