Tianzhi Chen

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MicroRNAs (miRNAs) play an important role in regulating almost all biological processes. miRNAs bind to the 3' untranslated region (UTR) of mRNAs by sequence matching. In a previous study, we demonstrated that miR-21 was differently expressed in alpaca skin with different hair color. However, the molecular and cellular mechanisms for miR-21 to regulate the(More)
MicroRNAs (miRNAs) play an essential role in the regulation of almost all the biological processes, including melanogenesis. MiR-27a-3p is nearly six times higher in white alpaca skin compared to brown skin, which indicates that miR-27a-3p may be a candidate regulator for melanogenesis. Wnt3a plays an important role in promoting melanoblasts to(More)
One of the major tasks in the design and optimization process of a new landing gear system for a lunar lander is to accurately determine the loads and energy absorption capability during the landing event. The works of this paper describes a new approach of landing impact dynamic analysis using nonlinear finite element method. Abaqus/Explicit, which is part(More)
Conventional plant transformation typically includes preparation of competent plant cells or tissues, delivery of foreign genes into cells, transformed cell selection with stable incorporated foreign genes, and regeneration of transformed cells into intact plants. This process traditionally relies on tissue culture, and cotton has not been an exception to(More)
INTRODUCTION To investigate whether the membrane-associated transporter protein SLC45A2 is differentially expressed in the skin of sheep with different coat colors and to determine its correlation with coat color establishment in sheep. MATERIAL AND METHODS The expression of SLC45A2 in sheep skin samples with different coat colors was qualitatively and(More)
To investigate whether ocular albinism type 1 (OA1) is differentially expressed in the skin of mice with different coat colors and to determine its correlation with coat color establishment in mouse, the expression patterns and tissue distribution characterization of OA1 in the skin of mice with different coat colors were qualitatively and quantitatively(More)
Fibroblast growth factor 21 (FGF21) is known as a metabolic regulator to regulate the metabolism of glucose and lipids. However, the underlying mechanism of FGF21 on melanin synthesis remains unknown. Therefore, the current study investigates the effect of FGF21 on melanogenesis in alpaca melanocytes. We transfected the FGF21 into alpaca melanocytes, then(More)
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