Tianzeng Li

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The mechanism and biological effects of comparing recombinant human epidermal growth factor (rhEGF) with recombinant human basic fibroblast growth factor (rhβFGF) were evaluated on the model of incised wounds on ventral side of rabbit's ears in order to direct their medication in clinical. Total of 72 incised wounds on ventral side of 24 New Zealand(More)
OBJECTIVE To investigate the effects of asiaticoside on the proliferation and the Smad signal pathway of the hypertrophic scar fibroblasts. METHODS The hypertrophic scar fibroblasts were cultured with tissue culture method. The expressions of Smad2 and Smad7 mRNA after asiaticoside treatment were determined by reverse transcription-polymerase chain(More)
OBJECTIVE To investigate the inhibitory effect of Col I A1 antisense oligodeoxynucleotide (ASODN) transfection mediated by cationic liposome on Col I A1 expression in human hypertrophic scar fibroblasts. METHODS Scar tissue was obtained from volunteer donor. Human hypertrophic scar fibroblasts were cultured by tissue block method. The cells at passage 4(More)
UNLABELLED Objective Col I A1 antisense oligodeoxynucleotide (ASODN) has inhibitory effect on collagen synthesis in cultured human hypertrophic scar fibroblasts. To investigate the effects of intralesional injection of Col I A1 ASODN on collagen synthesis in human hypertrophic scar transplanted nude mouse model. METHODS The animal model of human(More)
BACKGROUND Antisense nucleic acids are effective in inhibiting harmful or uncontrolled gene expression. We had previously proved that the antisense DNA to type I collagen could effectively inhibit the synthesis of collagen type I in cultured hypertrophic scar fibroblasts, suggesting a potential role in anti-scarring, but there are no published reports of(More)
OBJECTIVE To investigate the bacterial epidemiology in our department in recent years, so as to provide assistance to the clinical management of burn patients. METHODS A retrospective analysis was carried out with 345 bacterial cultures from burn wound and drug-sensitivity results in 784 burn patients during 1993 to 1999 in our department. RESULTS (1)(More)
BACKGROUND Basic fibroblast growth factor (bFGF) was clinically proven to accelerate acute and chronic wound healing. Accelerated wound healing may lead to improved scarring. These studies suggested a possible antiscarring effect of bFGF during wound healing. Little was known about the precise pathologic mechanisms of bFGF on scarring formation. AIMS The(More)
The purpose of this study is to analyze the motion status of swimmers during their gliding stage using a numerical simulation method. This simulation strategy is conducted by solving the 3D incompressible Navier-Stokes equations using the Realizable k-ε turbulence closure equations in combination with the Six Degrees of Freedom (6-DOF) method. The uneven(More)
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