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PROTINFO: new algorithms for enhanced protein structure predictions

• Ling-Hong Hung, Shing-Chung Ngan, Tianyun Liu, Ram Samudrala
• Nucleic Acids Research
• 2005

We describe new algorithms and modules for protein structure prediction available as part of the PROTINFO web server. The modules, comparative and de novo modelling, have significantly improved… (More)

CRALBP ligand and protein interactions.

• Zhiping Wu, Sanjoy K Bhattacharya, +6 authors John W. Crabb
• Advances in experimental medicine and biology
• 2006

Scaffold proteins and the regeneration of visual pigments.

• Maria Nawrot, Tianyun Liu, Gregory G. Garwin, John W. Crabb, J. Saari
• Photochemistry and photobiology
• 2006

CRALBP, cellular retinaldehyde-binding protein, is a retinoid-binding protein necessary for efficient regeneration of rod and cone visual pigments. The C terminus of CRALBP binds to the PDZ domains… (More)

Predicting drug side-effects by chemical systems biology

• Nicholas P. Tatonetti, Tianyun Liu, Russ B. Altman
• Genome Biology
• 2009

New approaches to predicting ligand similarity and protein interactions can explain unexpected observations of drug inefficacy or side-effects.

Identification of recurring protein structure microenvironments and discovery of novel functional sites around CYS residues

• Shirley Wu, Tianyun Liu, Russ B. Altman
• BMC Structural Biology
• 2009

The emergence of structural genomics presents significant challenges in the annotation of biologically uncharacterized proteins. Unfortunately, our ability to analyze these proteins is restricted by… (More)

Scoring functions for de novo protein structure prediction revisited.

• Shing-Chung Ngan, Ling-Hong Hung, Tianyun Liu, Ram Samudrala
• Methods in molecular biology
• 2008

De novo protein structure prediction methods attempt to predict tertiary structures from sequences based on general principles that govern protein folding energetics and/or statistical tendencies of… (More)

Peroxisome proliferator-activated receptor gamma (PPARG) rs1801282 C>G polymorphism is associated with cancer susceptibility in asians: an updated meta-analysis.

• Yafeng Wang, Yu Chen, +5 authors Zhiqiang Ma
• International journal of clinical and…
• 2015

Peroxisome proliferator-activated receptor gamma (PPARG) is related to inflammation and plays an important role in the development of cancer. PPARG rs1801282 C>G polymorphism might influence the risk… (More)

“Genotype-first” approaches on a curious case of idiopathic progressive cognitive decline

• Lingling Shi, Bingxiao Li, +5 authors Kai Wang
• BMC Medical Genomics
• 2014

In developing countries, many cases with rare neurological diseases remain undiagnosed due to limited diagnostic experience. We encountered a case in China where two siblings both began to develop… (More)

Homo-dimerization and ligand binding by the leucine-rich repeat domain at RHG1/RFS2 underlying resistance to two soybean pathogens

• Ahmed J. Afzal, Ali Y. Srour, +7 authors David A Lightfoot
• BMC Plant Biology
• 2012

The protein encoded by GmRLK18-1 (Glyma_18_02680 on chromosome 18) was a receptor like kinase (RLK) encoded within the soybean (Glycine max L. Merr.) Rhg1/Rfs2 locus. The locus underlies resistance… (More)

Comparative modeling: the state of the art and protein drug target structure prediction.

• Tianyun Liu, Grace W. Tang, Emidio Capriotti
• Combinatorial chemistry & high throughput…
• 2011

The goal of computational protein structure prediction is to provide three-dimensional (3D) structures with resolution comparable to experimental results. Comparative modeling, which predicts the 3D… (More)

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