Tianying Wang

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T WENTY-FIVE years ago, F-actin was discovered to be the major component of microfilaments in animal cells (36). Since then, actin has been found in virtually all eukaryotic cells. What functions do microfilaments perform? Studies in animal cells have provided us with a picture of F-actin as the backbone of many structurally and functionally diverse(More)
MicroRNAs (miRNAs) are small non-coding RNAs that can posttranscriptionally regulate gene expression by targeting messenger RNAs. During miRNA biogenesis, the star strand (miRNA*) is generally degraded to a low level in the cells. However, certain miRNA* express abundantly and can be recruited into the silencing complex to regulate gene expression. Most(More)
Stress granules (SGs) are granular aggregates in the cytoplasm that are formed under a variety of stress situations including viral infection. Previous studies indicate that poliovirus, a member of Picornaviridae, can induce SG formation. However, the exact mechanism by which the picornaviruses induce SG formation is unknown. The localization of SG markers(More)
Human enterovirus 71 (EV71) is the main causative pathogen of hand, foot, and mouth disease (HFMD) in children. The epidemic of HFMD has been a public health problem in Asia-Pacific region for decades, and no vaccine and effective antiviral medicine are available. Curcumin has been used as a traditional medicine for centuries to treat a diversity of(More)
In this work, a metallic probe with a sharp tip and two half-circular nanostructures on its base is introduced and investigated. The proposed design aims at improving the detection performance of a probe for scattering scanning near-field optical microscopy in terms of enhanced signal-to-noise ratio. Under the premise of processing feasibility, the(More)
Coxsackievirus B (CVB) belongs to Enterovirus genus within the Picornaviridae family, and it is one of the most common causative pathogens of viral myocarditis in young adults. The pathogenesis of myocarditis caused by CVB has not been completely elucidated. In CVB infection, autophagy is manipulated to facilitate viral replication. Here we report that(More)
A Gram-stain positive, rod-shaped, endospore-forming and aerobic bacterium, designated BZ1T, was isolated from a soil sample collected from a sunflower field in Wuyuan county, Inner Mongolia, China. On the basis of 16S rRNA gene sequence analysis, the isolate was found to be a member of the genus Bacillus and the close phylogenetic relatives to be Bacillus(More)
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