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—Being able to keep the graph scale small while capturing the properties of the original social graph, graph sampling provides an efficient, yet inexpensive solution for social network analysis. The challenge is how to create a small, but representative sample out of the massive social graph with millions or even billions of nodes. Several sampling(More)
The host innate immune response to viral infections often involves the activation of parallel pattern recognition receptor (PRR) pathways that converge on the induction of type I interferons (IFNs). Several viruses have evolved sophisticated mechanisms to attenuate antiviral host signaling by directly interfering with the activation and/or downstream(More)
Recent work in security and systems has embraced the use of machine learning (ML) techniques for identifying misbehavior, e.g. email spam and fake (Sybil) users in social networks. However, ML models are typically derived from fixed datasets, and must be periodically retrained. In adversarial environments, attackers can adapt by modifying their behavior or(More)
The microtubule-associated protein, tau, is a highly soluble molecule that is nonetheless capable of self-association into filamentous deposits characteristic of a number of neurodegenerative diseases. This state change is thought to be driven by phosphorylation and/or C-terminal truncation events resulting in intracellular inclusions, such as the(More)
Social interactions and interpersonal communication has undergone significant changes in recent years. Increasing awareness of privacy issues and events such as the Snowden disclosures have led to the rapid growth of a new generation of anonymous social networks and messaging applications. By removing traditional concepts of strong identities and social(More)
Adipose tissue macrophages (ATMs) play a critical role in obesity-induced inflammation and insulin resistance. Distinct subtypes of ATMs have been identified that differentially express macrophage galactose-type C-type lectin 1 (MGL1/CD301), a marker of alternatively activated macrophages. To evaluate if MGL1 is required for the anti-inflammatory function(More)
Nowadays, Online Social Networks (OSNs) have become dramatically popular and the study of social graphs attracts the interests of a large number of researchers. One critical challenge is the huge size of the social graph, which makes the graph analyzing or even the data crawling incredibly time consuming, and sometimes impossible to be completed. Thus,(More)
  • Amit S. Paranjape, Roman Kuranov, Stepan Baranov, Li Leo Ma, Joseph W. Villard, Tianyi Wang +4 others
  • 2010
Application of photothermal Optical Coherence Tomography (OCT) to detect macrophages in ex vivo rabbit arteries which have engulfed nanoclusters of gold coated iron oxide (nanorose) is reported. Nanorose engulfed by macrophages associated with atherosclerotic lesions in rabbit arteries absorb incident laser (800nm) energy and cause optical pathlength (OP)(More)
  • Kanakadurga Singer, David L. Morris, Kelsie E. Oatmen, Tianyi Wang, Jennifer DelProposto, Taleen Mergian +2 others
  • 2013
Neuropeptide Y (NPY) is induced in peripheral tissues such as adipose tissue with obesity. The mechanism and function of NPY induction in fat are unclear. Given the evidence that NPY can modulate inflammation, we examined the hypothesis that NPY regulates the function of adipose tissue macrophages (ATMs) in response to dietary obesity in mice. NPY was(More)