Tianxiang Gu

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To assess the effect of basic fibroblast growth factor-binding extracellular matrix (bFGF-ECM) combined with bone marrow mesenchymal stem cells (BMSCs) transplantation on acute myocardial infarction (AMI) and explore the underlying mechenisms. Rabbit hearts were processed by decellularization with sodium dodecyl sulfate (SDS) perfusion, heparin(More)
OBJECTIVE To investigate the effects and mechanisms of panaxoside Rg1 on the new vessel formation in acute myocardial infarction (AMI) rats. METHODS The AMI model of male Sprague-Dawley (SD) rats was established, and rats were randomly divided into the AMI model group, the treatment group of panaxoside Rg1, the placebo group and the treatment group of(More)
BACKGROUND The efficacy of continuous retrograde del Nido cardioplegia for myocardial protection is still controversial. We hypothesised that antegrade and retrograde cardioplegia offer equivalent safety for myocardial protection in the David I procedure. METHODS We retrospectively reviewed 33 patients undergoing the David I operation with antegrade or(More)
OBJECTIVE To explore the role of microRNA (miR)-30a in the development of aortic dissection. METHODS Human aortic specimens of aortic dissections and aneurysms were harvested. Aortic specimens from donors for heart transplantation served as controls. Rat aortic vascular smooth muscle cells (VSMCs) were transfected with agomiR-30a or antagomiR-30a, and(More)
Cardiac hemangioma is a rare primary cardiac tumor. We reported the case of patient with left ventricular hemangioma who was referred to our hospital complaining of palpitation for one week. 24 h Holter revealed high episode of ventricular arrhythmia. Echocardiography showed a mass at left ventricle, which was also confirmed by MRI. The mass was(More)
An 18-year-old female presented with fever, bilateral lower limb swelling, and exertional shortness of breath. Echocardiography demonstrated a large pericardial effusion and a solid tumor that was anterior to the right ventricle (Figs. 1 and 2). Computed tomography further revealed a large pericardial effusion with small bilateral effusions (Fig. 3). A(More)
OBJECTIVE Mitophagy results in selective clearance of damaged mitochondria. We investigated whether mitophagy was involved in the neuroprotection by inhibiting microRNA (miRNA)-124 on ischemic spinal cords. METHODS Inhibition of miRNA-124 was conducted by intrathecal injection of lentivirus vectors containing antagomiR-124. Spinal cord ischemia was(More)