Tianming Yang

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Our brains allow us to reason about alternatives and to make choices that are likely to pay off. Often there is no one correct answer, but instead one that is favoured simply because it is more likely to lead to reward. A variety of probabilistic classification tasks probe the covert strategies that humans use to decide among alternatives based on evidence(More)
Performance in visual discrimination tasks improves with practice. Although the psychophysical parameters of these improvements have suggested the involvement of early areas in visual cortex, there has been little direct study of the physiological correlates of such perceptual learning at the level of individual neurons. To examine how neuronal response(More)
Previous studies have shown that perceptual learning can substantially alter the response properties of neurons in the primary somatosensory and auditory cortices. Although psychophysical studies suggest that perceptual learning induces similar changes in primary visual cortex (V1), studies that have measured the response properties of individual neurons(More)
A decision is a commitment to a proposition among multiple options. Often this commitment leads to a particular course of action. It might be said that the life of an organism consists of a series of decisions made in time [29]. Leaving aside the moral dimension of choices, it is reasonable to view even pedestrian decisions as a window on higher cognitive(More)
  • LibraryD . Andresen, Larry Carver, +12 authors Q . ZhengAlexandria
  • 1995
The Alexandria Digital Library (ADL) is focussed on providing broad access to distributed collections of spatially-indexed information. ADL has a four-component architecture involving collections , catalog, interfaces, and ingest facilities. The rst stage in the construction of ADL resulted in the design and implementation of a rapid prototype (RP) system.(More)
Difficult decisions often require evaluation of samples of evidence acquired sequentially. A sensible strategy is to accumulate evidence, weighted by its reliability, until sufficient support is attained. An optimal statistical approach would accumulate evidence in units of logarithms of likelihood ratios (logLR) to a desired level. Studies of perceptual(More)
ZD7288 has been widely used as a tool in the study of hyperpolarization-activated cyclic nucleotide-gated channels (HCN channels), and to test the relationships between HCN channels and heart and brain function. ZD7288 is widely considered a selective blocker of HCN currents. Here we show that ZD7288 inhibits not only HCN channel currents, but also Na(+)(More)
The subgenual anterior cingulate cortex (subgenual ACC) plays an important role in regulating emotion, and degeneration in this area correlates with depressed mood and anhedonia. Despite this understanding, it remains unknown how this part of the prefrontal cortex causally contributes to emotion, especially positive emotions. Using Pavlovian conditioning(More)
The evolution of neural activity during a perceptual decision is well characterized by the evidence parameter in sequential sampling models. However, it is not known whether accumulating signals in human neuroimaging are related to the integration of evidence. Our aim was to determine whether activity accumulates in a nonperceptual task by identifying brain(More)
Driven by the increasing demand for large-scale and high-performance data protection, disk-based de-duplication storage has become a new research focus of the storage industry and research community where several new schemes have emerged recently. So far these systems are mainly inline de-duplication approaches, which are centralized and do not lend(More)